Aspergillus Galactomannan Antigen by EIA, Serum
Also known as: ASPERAG
Use
The Aspergillus Galactomannan Antigen by EIA, Serum test aids in the diagnosis of invasive or disseminated aspergillosis. This test is used as a diagnostic aid in patients suspected of having invasive aspergillosis, particularly in high-risk patients where early detection is critical. It involves measuring the presence of galactomannan, a molecule found in the fungal cell wall of Aspergillus species, and helps in the identification of fungal infections which could be life-threatening in immunocompromised individuals.
Special Instructions
Not provided.
Limitations
Negative results do not rule out the possibility of invasive aspergillosis, and further testing should be considered, especially in high-risk or symptomatic patients. Single positive test results require correlation with additional clinical findings and possibly a repeat test due to potential cross-reaction with non-fungal substances like certain foods and antibiotics. False positives are more common in children compared to adults, affecting the reliability of results in pediatric populations. Additionally, plasma and hemolyzed specimens are unacceptable and may lead to test errors.
Methodology
Immunoassay (EIA)
Biomarkers
Aspergillus Galactomannan Antigen
AnalyteAspergillus Galactomannan Index
Analyte
LOINC Codes
- 44099-0 - Galactomannan Ag SerPl Ql IA
- 62467-6 - Galactomannan Ag Spec IA-aCnc
Result Turnaround Time
1-2 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
2 mL
Minimum Volume
1 mL
Container
ARUP Sterile Transport Tube
Collection Instructions
Separate serum from cells within 2 hours of collection and transfer to a transport tube.
Causes for Rejection
Plasma, hemolyzed specimens
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Unacceptable |
| Refrigerated | 1 week |
| Frozen | 1 week |
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