C-Telopeptide, Beta-Cross-Linked, Serum
Also known as: CTX
Use
The C-Telopeptide, Beta-Cross-Linked, Serum test is primarily used to measure bone resorption and to monitor the efficacy of antiresorptive therapy, such as bisphosphonates and hormone replacement therapy, in postmenopausal women and individuals with osteoporosis. This test helps in assessing bone turnover in different age and gender groups to support the management of osteoporosis.
Special Instructions
Fasting specimen is preferred, and a morning collection is advised for optimal results. The serum separator tube should sit for 15-20 minutes at room temperature for proper clot formation before processing.
Limitations
Hemolyzed specimens and green lithium heparin plasma are considered unacceptable. It is important to separate serum or plasma from cells as soon as possible and within 2 hours of collection to ensure the accuracy of results. The stability of the separated sample varies depending on the storage temperature, with a maximum frozen stability of 3 months.
New York Approved
Methodology
Immunoassay (ECLIA)
Biomarkers
LOINC Codes
- 41171-0
Result Turnaround Time
1 day
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Allow serum separator tube to sit for 15-20 minutes at room temperature for proper clot formation. Centrifuge and separate serum or plasma from cells ASAP or within 2 hours of collection.
Patient Preparation
Fasting specimen preferred.
Causes for Rejection
Hemolyzed specimens, Green lithium heparin plasma
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 24 hours |
| Refrigerated | 48 hours |
| Frozen | 3 months |