Collagen Type I C-Telopeptide (CTx)
Use
CTX is useful to assess bone resorption in patients with metabolic bone disease. The test is also useful in monitoring therapy to slow or halt osteoporotic bone loss.
Special Instructions
Not provided.
Limitations
Not provided.
Methodology
Immunoassay (IA)
Biomarkers
Result Turnaround Time
4 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
transport tube
Collection Instructions
Allow blood to clot (30-60 minutes) at room temperature. Centrifuge and separate the serum from the cells and transfer serum to a clean transport tube. Freeze as soon as possible.
Patient Preparation
A minimum of 12 hours fasting is required. Fasting morning collection 8‑10 am (Diurnal variations cause elevated levels at night). Dietary supplements containing biotin may interfere in assays and may skew results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega‑doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation.
Causes for Rejection
Moderate to gross hemolysis • Grossly lipemic • Gross icteric
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 16 hours |
| Refrigerated | 72 hours |
| Frozen | 90 days |