C-Telopeptide (Endocrine Sciences)

Also known as: Carboxyterminal Cross-linking Telopeptide of Bone Collagen, Collagen Cross-linked C-Telopeptide, Crosslaps, Type 1 Collagen

Clinical Use

Order Test

Use

For in vitro diagnostic use as an indicator of human bone resorption. This test may be used as an aid in monitoring bone resorption changes of antiresorptive therapies in postmenopausal women, individuals with osteopenia, and in predicting skeletal response (bone mineral density) in postmenopausal women undergoing antiresorptive therapies.

Special Instructions

Not provided.

Limitations

This test is not intended to predict the development of osteoporosis or future fracture risk. The use of this test has not been established in hyperparathyroidism or hyperthyroidism. When using the test to monitor therapy, results may be confounded in patients afflicted with clinical conditions known to affect bone resorption. Results should be interpreted in conjunction with clinical findings and other diagnostic results and should not be used as a sole determination in initiating or changing therapy. Note: Serum values are not interchangeable with urine values.

Test Details

Methodology

Immunoassay (ECLIA)

Biomarkers

C-Telopeptide

Analyte

C-Telopeptide

Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

LOINC Codes

Order Codes

41171-0 - Collagen CTx SerPl-mCnc

Result Codes

41171-0 - Collagen CTx SerPl-mCnc

Result Turnaround Time

3-5 days

Specimen

Serum

Volume

0.5 mL

Minimum Volume

0.3 mL

Container

Gel-barrier tube

Collection Instructions

It is recommended to draw blood as fasting, morning samples. Separate serum from cells within 45 minutes of collection. Transfer specimen to a plastic transport tube before freezing.