CD52 (CAMPATH-1) by Immunohistochemistry

Also known as: CD52 IHC

Clinical Use

Use

The CD52 (CAMPATH-1) test by Immunohistochemistry is used for the detection and visualization of the CD52 antigen in tissue or cell samples. CD52 is a glycoprotein expressed on the surface of mature lymphocytes, monocytes, and some macrophages, making it useful for diagnosing and differentiating lymphoid neoplasms and certain other hematological conditions. This test helps in the assessment of immune-related pathologies and can assist in the identification of therapeutic targets for conditions such as chronic lymphocytic leukemia.

Special Instructions

Not provided.

Limitations

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test is performed in a CLIA certified laboratory and is intended for clinical purposes. The test result interpretation is dependent on the quality and preservation of the specimen submitted. Non-representative tissues or depleted specimens may lead to invalid results.

Test Details

New York Approved

Methodology

Immunoassay (IHC)

Biomarkers

CD52

Protein

IHC

Expression • Categorical (e.g., Positive / Negative / Indeterminate)

LOINC Codes

Result Codes

94736-6 - Tissue block ID Spec

Result Turnaround Time

1-3 days

Specimen

Tissue (FFPE)

Volume

Not provided

Minimum Volume

2 slides

Container

Tissue block or 5 unstained (3- to 5-micron thick sections), positively charged slides in a tissue transport kit

Collection Instructions

Formalin fix (10 percent neutral buffered formalin) and paraffin embed specimen. Protect paraffin block and/or slides from excessive heat. Transport tissue block or slides in a tissue transport kit. If sending precut slides, do not oven bake.