Claudin-4 by Immunohistochemistry
Also known as: CLAUD4 IHC
Use
The Claudin-4 by Immunohistochemistry test is used to detect the presence of Claudin-4 protein in tissue or cell samples. This test aids in the diagnosis and differentiation of tumors, as Claudin-4 is commonly expressed in various epithelial-derived cancers. Its presence can be indicative of certain types of malignancies, making it a valuable tool in oncological pathology for guiding treatment decisions.
Special Instructions
Not provided.
Limitations
The Claudin-4 immunohistochemistry test is performed as a stain and return technical service; it does not provide quantitative results. This laboratory-developed test has not been cleared or approved by the FDA, and its performance characteristics were determined by ARUP Laboratories in a CLIA-certified environment. The results must be interpreted within the context of the specific clinical scenario, and nonrepresentative tissue samples or depleted specimens may lead to inaccurate or inconclusive results.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
Claudin-4
Protein
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
2 slides
Container
Tissue block or positively charged slides
Collection Instructions
Formalin fix (10 percent neutral buffered formalin) and paraffin embed specimen. Transport tissue block or 5 unstained (3-5 micron thick sections), positively charged slides in a Tissue Transport Kit. Protect from excessive heat. If sending precut slides, do not oven bake.
Storage Instructions
Room temperature, protect from excessive heat. Ship in cooled container during summer months.
Causes for Rejection
Specimens with nonrepresentative tissue type, depleted specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinitely |
| Refrigerated | Indefinitely |
| Frozen | Unacceptable |
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