Cotinine Screen, Urine
Also known as: COTININE
Use
This urine screening test is used for determining active exposure to nicotine and compliance with smoking-cessation programs. It serves as a presumptive test to evaluate whether individuals have been exposed to nicotine either through direct tobacco use, nicotine replacement therapy, or passive inhalation (second-hand smoke). For more detailed analysis or differentiation between nicotine replacement therapy and tobacco use, the 'Nicotine and Metabolites, Urine, Quantitative' test is preferred.
Special Instructions
Not provided.
Limitations
A presumptive positive result by immunoassay does not confirm the presence of nicotine. False positives may occur, and confirmatory testing by mass spectrometry is recommended if necessary. Repeated freeze/thaw cycles may compromise the integrity of samples and lead to unreliable results.
Methodology
Immunoassay (ELISA)
Biomarkers
Cotinine
Analyte
LOINC Codes
- 12293-7 - Cotinine Ur Ql
Result Turnaround Time
1-5 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
4 mL
Minimum Volume
2 mL
Container
ARUP standard transport tube
Collection Instructions
Transfer 4 mL urine with no additives to the ARUP standard transport tube.
Storage Instructions
Refrigerated
Causes for Rejection
Specimens exposed to repeated freeze/thaw cycles
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 10 days |
| Refrigerated | 10 days |
| Frozen | 8 months |
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