Creatinine Clearance, Urine

Also known as: CRTCL

Clinical Use

Use

The Creatinine Clearance test is a measure of kidney function by evaluating how well creatinine is removed from the blood by the kidneys. Determining the creatinine clearance rate can help diagnose kidney problems, as a decreased clearance rate indicates that the kidneys are not functioning properly, which could be a result of conditions such as chronic kidney disease or acute kidney injury. This test is commonly used to monitor patients with kidney issues and to adjust medication dosages accordingly.

Special Instructions

Not provided.

Limitations

The accuracy of the Creatinine Clearance test can be affected by incomplete urine collection or incorrect timing of blood collection relative to urine collection. Random urine collections are unacceptable, as accurate timing is crucial for valid test results. Other factors such as diet, hydration status, and body mass can influence creatinine levels and clearance calculations, potentially leading to misleading results if not accounted for in clinical evaluation. Additionally, the test may not accurately reflect kidney function in very young, elderly, or severely ill patients without additional diagnostic context.

Test Details

FDA Approved

New York Approved

Methodology

Automated Analyzer (Clinical Chemistry)

Biomarkers

5 components

Creatinine, Urine - per volume • Clinical ChemistryCreatinine Clearance - per volume • Clinical ChemistryCreatinine, Serum - per volume • Clinical ChemistryTotal Volume • Clinical Chemistry+1 more