HLA Antibody Screen, Class I and Class II

Also known as: HLAABSCN

Clinical Use

Use

This test is used to detect HLA antibodies for solid organ and stem cell transplantation. The presence or absence of HLA Class I and Class II IgG antibodies is determined, providing important immunological information necessary for the management of transplant patients.

Special Instructions

Not provided.

Limitations

The test only detects IgG antibody isotype and does not detect IgM antibodies. It does not provide information on the specificities of the HLA antibodies detected. The test was developed under accreditation guidelines from the American Society for Histocompatibility and Immunogenetics (ASHI), but some tests or reagents have not been cleared or approved by the FDA.

Test Details

Methodology

Immunoassay (Multiplex Protein Panel)

Biomarkers

3 components

HLA Class I Antibody • Multiplex Protein PanelHLA Class II Antibody • Multiplex Protein PanelHLA Antibody Screen Interpretation • Multiplex Protein Panel

LOINC Codes

Result Codes

72322-1 - HLA-A+B+C IgG SerPl Ql IA
62364-5 - Test performance info Spec

Result Turnaround Time

3-7 days

Specimen

Serum

Volume

5 mL

Minimum Volume

2 mL

Container

ARUP Standard Transport Tubes

Collection Instructions

Transfer 5 mL serum to ARUP Standard Transport Tubes. (Min. 2 mL) New York State Clients: Transfer 7 mL serum to ARUP Standard Transport Tubes. (Min. 3 mL)