Mumps Virus Antibody, IgG
Also known as: MUMPS
Use
The Mumps Virus Antibody, IgG test is used to determine if a person has immunity to the mumps virus either from previous infection or from vaccination. A positive result indicates the presence of IgG antibodies to the mumps virus, suggesting either a current or past exposure or immunization. It is not recommended as a stand-alone test but is useful for assessing immunization status or confirming a suspected past infection. The best evidence of current infection comes from a significant change in antibody levels on paired specimens tested concurrently in the same laboratory.
Special Instructions
Parallel testing with specimens labeled as acute or convalescent is preferred. Convalescent specimens should be received within 30 days from receipt of acute specimens for optimal comparative analysis. Allow specimens to clot completely at room temperature before processing.
Limitations
This test should not be used as a sole diagnostic tool for current mumps infection due to the potential for cross-reactivity with antibodies to other viruses. It is most reliable when there is a significant change in antibody levels demonstrated on two appropriately timed specimens. False negatives may occur if the sample is taken too early before the development of IgG antibodies, or due to compromised specimen conditions.
Methodology
Immunoassay (CLIA)
Biomarkers
LOINC Codes
- 25418-5
Result Turnaround Time
1 day
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
Serum separator tube (SST)
Collection Instructions
Allow the specimen to clot completely at room temperature. Separate from cells ASAP or within 2 hours of collection.
Storage Instructions
Refrigerated transport is required.
Causes for Rejection
Contaminated, heat-inactivated, grossly hemolyzed, lipemic, or severely icteric specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 year (avoid repeated freeze/thaw cycles) |
