Streptococcus pneumoniae Antigen, Urine
Also known as: SPN AG
Use
Aid in the diagnosis of pneumococcal pneumonia, particularly when diagnosed in the context of community-acquired pneumonia (CAP). The test identifies the presence of Streptococcus pneumoniae antigens in urine, which can suggest an active infection that may require clinical intervention. It is especially useful for confirming suspected pneumonia cases where traditional cultures may not be feasible or are delayed.
Special Instructions
Patients who have received the S. pneumoniae vaccines may test positive within 48 hours following vaccination, so it is recommended to avoid testing within five days post-vaccination. Proper specimen handling includes mixing the urine specimen well and transferring it to the appropriate ARUP Standard Transport Tube for optimal results.
Limitations
False positives may occur due to cross-reactivity with other members of the S. mitis group. Therefore, clinical correlation is recommended to confirm the diagnosis. The test is qualitative and only provides a confirmation of the presence or absence of the antigen, but not the quantity present.
Methodology
Immunoassay (Lateral Flow)
Biomarkers
LOINC Codes
- 24027-5
Result Turnaround Time
1 day
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
4 mL
Minimum Volume
1 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Mix specimen well. Transfer 4 mL urine to an ARUP Standard Transport Tube.
Storage Instructions
Refrigerated or frozen.
Causes for Rejection
Specimen types other than urine.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 24 hours |
| Refrigerated | 2 weeks |
| Frozen | 2 weeks |
