Anti-Pancreatic Antibodies by Indirect Fluorescent Antibody (IFA) (RDL)
Also known as: PAB
Use
PAB has 90% specificity and 30% sensitivity for Crohn's Disease.
Special Instructions
This test is currently not approved for use in New York state. When submitting multiple tests on frozen samples, separate frozen specimens should be sent for each test requested to avoid any delays in turnaround time.
Limitations
Despite having high specificity, the sensitivity of pancreatic antibodies for Crohn's Disease is relatively low at 30%. Therefore, a negative result does not rule out the presence of the disease. Test results should be considered in conjunction with other clinical findings and diagnostic results. Further confirmatory or reflex testing may be required in certain cases.
Methodology
Immunoassay (Indirect Immunofluorescence)
Biomarkers
LOINC Codes
- 5265-4
- 5265-4
Result Turnaround Time
7-14 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.3 mL
Container
Red-top tube or gel-barrier tube
Collection Instructions
Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping.
Storage Instructions
Refrigerate or freeze.
Causes for Rejection
Grossly hemolyzed; bacterial contamination; lipemic specimen; icteric specimen; non-serum specimen types
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 14 days |
| Frozen | 60 days |