Apolipoprotein Assessment
Also known as: Alpha and Beta Apolipoproteins
Use
Studies have shown that the ratio of apolipoprotein A-1:apolipoprotein B may correlate better with increased risk of coronary artery disease (CAD) than total cholesterol, and LDL:HDL ratio.
Special Instructions
Not provided.
Limitations
Apolipoprotein measurements provide greater stability and discrimination in evaluating coronary artery disease risk compared to lipid levels, which are subject to biological variation. However, they do not establish a definite relationship between childhood apolipoprotein levels and adult coronary heart disease, and further studies are required to fully understand this correlation.
Methodology
Immunoassay
Biomarkers
Apolipoprotein A-1
ProteinApolipoprotein B
ProteinApolipoprotein B:A-1 Ratio
Other
LOINC Codes
- 55724-9 - Apol A-I+A-II+B+C Pnl SerPl-mCnc
- 1869-7 - Apo A-I SerPl-mCnc
- 1884-6 - Apo B SerPl-mCnc
- 1874-7 - Apo B/Apo A-I SerPl
Result Turnaround Time
1-2 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
4 mL
Minimum Volume
Not provided
Container
Red-top tube, gel-barrier tube
Collection Instructions
Separate serum or plasma from cells within 45 minutes. Transfer specimen to a plastic transport tube.
Patient Preparation
Patient must be fasting 12 to 14 hours.
Storage Instructions
Maintain specimen at room temperature.
Causes for Rejection
Specimen from nonfasting patient
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |
Other tests from different labs that may be relevant