C-Peptide, Three Specimens

Clinical Use

Use

The C-Peptide, Three Specimens test is used primarily in the evaluation of patients with fasting hypoglycemia to differentiate between insulin-secreting tumors (insulinomas) and exogenous insulin administration. It is also used to monitor the insulin production of beta cells in diabetes management. By measuring the amount of C-peptide produced, healthcare providers can assess the functionality of a patient's insulin-producing beta cells.

Special Instructions

Not provided.

Limitations

Test results may exhibit interference from patients consuming high doses of biotin, which could lead to inaccurate results. Therefore, patients should be questioned regarding their intake of biotin or related supplements and advised accordingly. Further testing or confirmatory tests may be necessary depending on initial results which may affect overall turnaround time.

Test Details

Methodology

Automated Analyzer (Clinical Chemistry)

Biomarkers

C-Peptide

Analyte

C-Peptide #1

Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

C-Peptide #2

Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

C-Peptide #3

Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

LOINC Codes

Order Codes

13032-8 - C peptide sp2 p chal SerPl-mCnc
13033-6 - C peptide sp3 p chal SerPl-mCnc
46963-5 - Tube # SerPlBld
57376-6 - C peptide BS SerPl-mCnc

Result Codes

57376-6 - C peptide BS SerPl-mCnc
46963-5 - Tube # SerPlBld
13032-8 - C peptide sp2 p chal SerPl-mCnc
13033-6 - C peptide sp3 p chal SerPl-mCnc

Result Turnaround Time

1-2 days

Specimen

Serum

Volume

Not provided

Minimum Volume

Not provided

Collection Instructions

Collect three serum specimens at appropriate intervals. It is critical that post-treatment samples are collected accurately following drug administration or treatment step.