Use

The test measures the free kappa and lambda light chains in the urine, along with the calculated kappa/lambda ratio. This is useful for identifying and monitoring lymphoproliferative disorders such as multiple myeloma, where abnormal levels of these light chains indicate disease presence or progression. An abnormal ratio in urine may suggest lymphoproliferative diseases, but serum tests are generally preferred for their sensitivity in detecting monoclonal gammopathy. Urine tests can be useful when serum tests are not conclusive or when high concentrations of polyclonal free light chains interfere with Bence Jones protein quantification.