Intrinsic Pathway Coagulation Factor Profile
Use
The Intrinsic Pathway Coagulation Factor Profile is utilized to assess the function of the intrinsic and common coagulation pathways by evaluating specific coagulation factors. This test is integral in diagnosing bleeding disorders and monitoring treatment efficacy in patients with hemophilia or other clotting factor deficiencies.
Special Instructions
Ensure proper specimen collection by following strict guidelines, including the use of citrated plasma collected by double centrifugation to maintain the integrity of the sample. Blue-top tubes must be filled to completion to achieve correct blood to anticoagulant ratios. Avoid using arms with heparin locks or heparinized catheters for specimen collection.
Limitations
This profile may not detect all subtleties of coagulation disorders as it evaluates only the intrinsic pathway factors. External factors such as improper specimen handling or collection can affect the test results. Reflex testing may be necessary for comprehensive diagnostic evaluation.
Methodology
Other
Biomarkers
LOINC Codes
- 3209-4
- 3187-2
- 3226-8
- 3232-6
Result Turnaround Time
2-3 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
2 mL
Minimum Volume
1 mL
Container
Blue-top (sodium citrate) tube
Collection Instructions
Citrated plasma samples should be collected by double centrifugation. Blood should be collected in a blue-top tube containing 3.2% buffered sodium citrate. Evacuated collection tubes must be filled to completion. Mix gently by inversion and freeze immediately after collection and preparation.
Patient Preparation
Do not draw from an arm with a heparin lock or heparinized catheter.
Storage Instructions
Freeze