Lipid Cascade With Reflex to Lipoprotein Particle Assessment by NMR (With Graph if Reflexed)

Clinical Use

Use

The lipid cascade supports risk assessment and management of patients who present with cardiometabolic risk (CMR) factors (e.g., elevated blood pressure, abdominal obesity, insulin resistance (IR), lipoprotein abnormalities and elevated blood glucose).

Special Instructions

Not provided.

Limitations

Testing is not performed if triglyceride levels exceed 800 mg/dL, as LDL cholesterol calculation is not applicable at such levels. Certain factors such as non-fasting status can affect insulin resistance scoring.

Test Details

Methodology

Other

Biomarkers

2 components

Lipid Profile • Clinical ChemistryLipoprotein Analysis

LOINC Codes

Order Codes

24331-1 - Lipid 1996 Pnl SerPl

Result Codes

2093-3 - Cholest SerPl-mCnc
2085-9 - HDLc SerPl-mCnc
11054-4 - LDLc/HDLc SerPl
43396-1 - NonHDLc SerPl-mCnc
2571-8 - Trigl SerPl-mCnc
13457-7 - LDLc SerPl Calc-mCnc
8251-1 - Service Cmnt-Imp
18262-6 - LDLc SerPl Direct Assay-mCnc
54434-6 - LDL SerPl-sCnc
49748-7 - HDL SerPl-sCnc
43727-7 - LDL Small SerPl-sCnc
17782-4 - LDL SerPl Qn
62255-5 - LP-IR score SerPl

Result Turnaround Time

1 day

Specimen

Serum

Volume

2 mL (each tube)

Minimum Volume

1 mL (each tube)

Container

Gel-barrier transport, green-top (heparin), or lavender-top (EDTA) tube

Collection Instructions

Separate serum or plasma from cells within 45 minutes of collection. Gently invert tube eight to 10 times, allow specimen to clot for 30 minutes, and centrifuge within two hours of collection.

Patient Preparation

Patient should be fasting for eight hours.

Storage Instructions

Keep refrigerated and ship with frozen cool packs. Stable at room temperature for six hours or refrigerated for 10 days. Do not freeze.

Causes for Rejection

Hemolysis, unspun specimens, plasma/serum contaminated with red cells, inappropriate containers, room temperature storage beyond 24 hours, specimen older than six days.