Lipid Panel With Apolipoprotein B (ApoB), GlycA (Inflammation), Diabetes Risk Index (DRI)
Use
This "Extended Lipid Panel" quantifies the components of a typical lipid panel (TC, HDL-C and TG) along with ApoB by nuclear magnetic resonance (NMR) spectroscopy using the Vantera NMR Clinical Analyzer. Results from the Extended Lipid Panel Assay can be used by physicians to assist in CVD risk assessment. The principal protein component of LDL particles, ApoB, has been shown to be associated with CVD and is also an important CVD risk factor.
Special Instructions
Patient fasting is not required, but fasting for 12-14 hours is recommended for conditions where triglyceride values provide diagnostic information, such as screening for familial hypercholesterolemia or confirming hypertriglyceridemia.
Limitations
Triglyceride levels above 800 mg/dL will not allow LDL cholesterol calculation. GlycA measurements vary slightly depending on the type of specimen tube used, potentially leading to differences in results. GlycA is influenced by a variety of health conditions and should not be interpreted without a complete clinical history. DRI measurements from plasma specimens are typically 8 points lower than serum specimens. Hemolysis may reduce GlycA concentrations by more than 10%.
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 2093-3
- 2571-8
- 2085-9
- 43396-1
- 13457-7
- 1884-6
- 82730-3
- 94560-0
- 2093-3
- 2571-8
- 2085-9
- 43396-1
- 13457-7
- 1884-6
- 82730-3
- 94560-0
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
Plain red-top tube
Collection Instructions
Collect specimen in plain red-top tube (no gel) and allow to clot upright at room temperature for 45 minutes. Centrifuge and transfer to a transport tube for storage at 2-8°C until shipped.
Patient Preparation
Patient fasting is not required; however, fast for 12-14 hours if screening for certain conditions.
Storage Instructions
Refrigerate
Causes for Rejection
Unspun LipoTube, unseparated plain red-top or EDTA tube, citrated plasma, hemolysis.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 1 day |
| Refrigerated | 8 days |
| Frozen | 14 days |