Casandra
Casandra Test Code QD90109Version 1 (DRAFT)
Performing Lab
Acetylcholine Receptor Binding Antibody
Clinical Use
Order TestUse
Detects binding antibodies to the acetylcholine receptor (anti‑AChR) by a quantitative radioimmunoassay in the sera of patients with Myasthenia Gravis (MG). About 80%–85% of patients with generalized MG and 50%–75% with ocular MG have anti‑AChR binding antibodies. Negative results reflex to MuSK and LRP4 antibodies, which are present in approximately 8%‑10% and 9.2%, respectively, of MG patients negative for binding AChR antibodies. These results guide further diagnostic evaluation in suspected MG patients.
Special Instructions
Not provided.
Limitations
Not provided.
Test Details
Methodology
Other
Biomarkers
Acetylcholine Receptor Binding Antibody
ProteinRadioimmunoassay
Other • Categorical (e.g., Positive / Negative / Indeterminate)
Result Turnaround Time
Not provided.
Related Documents
For more information, please review the documents below
Specimen Requirements
Specimen
Serum
Volume
2 mL (0.5 mL minimum)
Minimum Volume
Not provided
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