Use

Detects binding antibodies to the acetylcholine receptor (anti‑AChR) by a quantitative radioimmunoassay in the sera of patients with Myasthenia Gravis (MG). About 80%–85% of patients with generalized MG and 50%–75% with ocular MG have anti‑AChR binding antibodies. Negative results reflex to MuSK and LRP4 antibodies, which are present in approximately 8%‑10% and 9.2%, respectively, of MG patients negative for binding AChR antibodies. These results guide further diagnostic evaluation in suspected MG patients.