Acetylcholine Receptor (AChR) Antibodies, Complete Profile With Reflex to MuSK Antibodies
Also known as: ACHALL, AG, MYESTTH, Reflex Musk
Use
Test for the laboratory diagnosis of myasthenia gravis (MG)
Special Instructions
Not provided.
Limitations
The test has not been cleared or approved by the FDA, and the performance characteristics have been determined by LabCorp. In rare cases, AChR antibodies can be found in patients with other autoimmune disorders or with thymoma without MG. About 10% of MG patients may not have the causative autoantibody identified, and 15% of MG patients may have no measurable AChR antibodies, but instead have antibodies against MuSK.
Methodology
Immunoassay
Biomarkers
Acetylcholine Receptor Binding Antibody
ProteinAcetylcholine Receptor Blocking Antibody
ProteinAcetylcholine Receptor Modulating Antibody
Protein
LOINC Codes
- 11034-6 - AChR Bind Ab Ser-sCnc
- 11561-8 - AChR Block Ab Ser-aCnc
- 99062-2 - AChR Mod Ab Ser Ql FC
- 11034-6 - AChR Bind Ab Ser-sCnc
- 11561-8 - AChR Block Ab Ser-aCnc
- 99062-2 - AChR Mod Ab Ser Ql FC
Result Turnaround Time
2-7 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
4 mL divided into two tubes
Minimum Volume
2 mL
Container
Red-top tube or gel-barrier tube
Collection Instructions
Allow a minimum clotting time of 30 to 60 minutes with serum separation within 2 hours of collection. Send serum samples in a plastic transport tubes.
Patient Preparation
No isotopes administered 24 hours prior to venipuncture.
Storage Instructions
Refrigerate.
Causes for Rejection
Excessive hemolysis; chylous serum; recently administered radioisotopes; plasma specimen
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 13 days |
| Refrigerated | 13 days |
| Frozen | 13 days |
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