Calprotectin, Stool
Also known as: Crohn's Disease, Ulcerative Colitis, Inflammatory Bowel Disease, Irritable Bowel Syndrome
Use
Calprotectin is a non‐specific marker of bowel inflammation. It is a neutrophil protein detectable in stool following white blood cell migration into the intestine. Fecal calprotectin levels may assist in diagnosis of inflammatory bowel disease—such as Crohn's disease and ulcerative colitis—and aid in differentiating IBD from irritable bowel syndrome (IBS).
Special Instructions
Not provided.
Limitations
NSAIDs may cause elevated results.
Methodology
Immunoassay (CLIA)
Biomarkers
Calprotectin
Protein
Result Turnaround Time
Not provided.
Related Documents
For more information, please review the documents below
Specimen
Stool
Volume
3 grams solid stool
Minimum Volume
0.3 g
Container
Quest standard stool container without preservative or clean leak‑proof plastic screw‑cap container
Causes for Rejection
Specimen collected in a container with fixative or preservative; collected during surgical procedure; any specimen other than raw stool sample
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Stable for 6 days (not recommended) |
| Refrigerated | 7 days |
| Frozen | 28 days at -20 °C; 1 year at -70 °C |
Other tests from different labs that may be relevant