Drug Monitoring, Methamphetamine D/L Isomers, Urine
Also known as: Pain Management, Prescription Drug Monitoring
Use
This test measures the ratio of the D‑ and L‑isomers of methamphetamine in urine. The L‑isomer may reflect over‑the‑counter nasal decongestant products or metabolism of selegiline; the D‑isomer may reflect prescription methamphetamine or metabolism of benzphetamine, and is also the predominant form in illicit formulations. It is useful in distinguishing the source of methamphetamine exposure and monitoring drug adherence or illicit use. Quantitative results above cutoff are reported; below cutoff are reported as negative. Quantitative values cannot assess dose due to variable metabolism and excretion.
Special Instructions
Not provided.
Limitations
Quantitative results are unable to assess drug dose due to extensive metabolism and excretion patterns; detection reflects presence but not timing or dose. A single monitoring approach may not adequately capture overall use patterns; clinical interpretation should integrate other tools.
Methodology
Mass Spectrometry
Biomarkers
Result Turnaround Time
2-3 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
9 mL
Minimum Volume
3 mL
Container
Unpreserved urine collection container
Causes for Rejection
Preserved samples
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 5 days |
| Refrigerated | 14 days |
| Frozen | 30 days |