Eslicarbazepine
Also known as: Eslicarbazepine Acetate, Aptiom
Use
Monitoring eslicarbazepine (monohydroxyoxcarbazepine, MHD) serum or plasma levels helps clinicians avoid toxicity and provides a baseline for therapeutic drug monitoring. Individual concentrations should be interpreted in the context of clinical condition, treatment history, and prior levels. Therapeutic range is generally 3–35 µg/mL; toxic levels are above 40 µg/mL.
Special Instructions
Not provided.
Limitations
Not provided.
Methodology
Mass Spectrometry
Biomarkers
10-Hydroxycarbazepine
Analyte
LOINC Codes
- 31019-3 - 10OH-Carbazepine SerPl-mCnc
Result Turnaround Time
1-5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
Plain red‑top tube (no gel)
Collection Instructions
Serum must be separated from whole blood within 2 hours of collection.
Patient Preparation
Pre‑dose (trough) draw at steady‑state concentration.
Causes for Rejection
Gel separator tubes (SST), whole blood, sodium citrate (light blue), ACD or SPS (yellow‑top) tubes
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 6 weeks |
| Refrigerated | 6 weeks |
| Frozen | 90 days |
Other tests from different labs that may be relevant