Interleukin-2 Receptor Alpha Chain (IL-2Ra/CD25), Soluble
Also known as: sCD25, Soluble IL2-Receptor, CD25, IL 2R, Cytokine
Use
Measurement of soluble interleukin‑2 receptor alpha (sIL‑2Ra, CD25) in serum aids evaluation of immune activation. Elevated levels are observed in lymphoproliferative disorders, autoimmune lymphoproliferative syndrome, hemophagocytic lymphohistiocytosis, macrophage activation syndrome, sarcoidosis, and hematologic malignancies.
Special Instructions
Not provided.
Limitations
Not provided.
Methodology
Immunoassay (Other)
Biomarkers
Interleukin‑2 Receptor Alpha (IL‑2Ra/CD25), Soluble
Protein
Result Turnaround Time
1-9 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
Red top (no additive)
Collection Instructions
No biotin supplements 48 hours prior to blood draw. Collect at consistent time of day; single 1‑2 mL blood in red‑top tube.
Patient Preparation
No biotin supplements 48 hours prior to blood draw.
Causes for Rejection
Serum separator tube (SST); plasma; received at room temperature; received refrigerated
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Unacceptable |
| Refrigerated | 24 hours |
| Frozen | 30 days |
Other tests from different labs that may be relevant