Voltage-Gated Calcium Channel (VGCC), Type P/Q Antibody
Also known as: Lambert-Eaton Test
Use
The Voltage-Gated Calcium Channel (VGCC), Type P/Q Antibody test is used to detect the presence of VGCC antibodies in the blood, which are associated with various neurological conditions, such as Lambert-Eaton Myasthenic Syndrome and certain types of paraneoplastic neurological syndromes.
Special Instructions
Not provided.
Limitations
The test may not identify all cases of VGCC-related disorders as some patients may have antibodies below the detection threshold. It may also show cross-reactivity with other antibodies, leading to false positives or misinterpretation.
Methodology
Immunoassay (ELISA)
Biomarkers
VGCC Type P/Q
Protein
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
Serum Separator Tube
Collection Instructions
Collect blood in a serum separator tube. Allow the blood to clot at room temperature, then centrifuge and separate the serum.
Patient Preparation
Patient may be required to fast before specimen collection.
Storage Instructions
Refrigerate if the sample will not be tested immediately.
Causes for Rejection
Hemolyzed or lipemic samples.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 24 hours |
| Refrigerated | 72 hours |
| Frozen | 14 days |
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