Coxsackie A Antibodies (Serotypes 2, 4, 7, 9, 10 and 16), Serum
Also known as: COX A AB
Use
This test is used to detect the presence of antibodies against Coxsackie A virus serotypes 2, 4, 7, 9, 10, and 16 in the serum. These serotypes are commonly associated with hand, foot, and mouth disease and other enterovirus-related illnesses. The presence of antibodies can indicate a past or recent infection, with higher antibody titers suggesting recent infection.
Special Instructions
Not provided.
Limitations
Cross-reactivity can occur among enteroviruses, which means antibodies to non-target serotypes may be detected. Antibody levels may persist for only a few months, limiting the test's ability to detect past infections. Titers of 1:8 or 1:16 are not definitive for recent infection but suggest a possible past infection. A four-fold increase in titer between acute and convalescent samples confirms diagnosis.
Methodology
Immunoassay (Other)
Biomarkers
LOINC Codes
- 9753-5 - CV A2 Ab Titr Ser CF
- 9754-3 - CV A4 Ab Titr Ser CF
- 9755-0 - CV A7 Ab Titr Ser CF
- 9757-6 - CV A9 Ab Titr Ser CF
- 9750-1 - CV A10 Ab Titr Ser CF
- 6688-6 - CV A16 Ab Titr Ser CF
Result Turnaround Time
6-11 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
2 mL
Minimum Volume
1 mL
Container
ARUP standard transport tube
Collection Instructions
Transfer 2 mL serum to an ARUP standard transport tube.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 1 week |
| Refrigerated | 2 weeks |
| Frozen | 1 month |
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