Coxsackie A Antibodies (Serotypes 2, 4, 7, 9, 10 and 16), Serum
Also known as: COX A AB
Use
This test is used to detect the presence of antibodies against Coxsackie A virus serotypes 2, 4, 7, 9, 10, and 16 in the serum. These serotypes are commonly associated with hand, foot, and mouth disease and other enterovirus-related illnesses. The presence of antibodies can indicate a past or recent infection, with higher antibody titers suggesting recent infection.
Special Instructions
The test is not performed at ARUP Laboratories and requires that separate specimens be submitted if multiple tests are ordered. The testing is performed at a non-ARUP laboratory.
Limitations
Cross-reactivity can occur among enteroviruses, which means antibodies to non-target serotypes may be detected. Antibody levels may persist for only a few months, limiting the test's ability to detect past infections. Titers of 1:8 or 1:16 are not definitive for recent infection but suggest a possible past infection. A four-fold increase in titer between acute and convalescent samples confirms diagnosis.
New York Approved
Methodology
Immunoassay (Other)
Biomarkers
LOINC Codes
- 9753-5
- 9754-3
- 9755-0
- 9757-6
- 9750-1
- 6688-6
Result Turnaround Time
6-11 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
2 mL
Minimum Volume
1 mL
Container
ARUP standard transport tube
Collection Instructions
Transfer 2 mL serum to an ARUP standard transport tube.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 1 week |
| Refrigerated | 2 weeks |
| Frozen | 1 month |
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