Anti-Human Epithelial Antigen, Ber-EP4 by Immunohistochemistry
Also known as: BEREP4 IHC
Use
The Anti-Human Epithelial Antigen, Ber-EP4 test is used primarily for the identification of epithelial cells in tissue samples. This immunohistochemical assay is crucial in the differential diagnosis of carcinomas, as Ber-EP4 specifically stains epithelial cells, aiding in distinguishing them from mesothelial cells and other tissue types. The test contributes significantly to the pathological assessment and can guide clinical decision-making regarding patient management and treatment options.
Special Instructions
Not provided.
Limitations
This test is performed as a stain and return (technical) service only. The test was developed and its performance characteristics determined by ARUP Laboratories but has not been cleared or approved by the US Food and Drug Administration. As it's conducted in a CLIA certified laboratory, the results should be interpreted within the scope of a laboratory-developed test. Samples that are not representative or are depleted are considered unacceptable.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
EpCAM
Protein
LOINC Codes
- 47010-4 - BER-EP4 Ag Tiss Ql ImStn
- 94736-6 - Tissue block ID Spec
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
2 slides
Container
Transport tissue block or 5 unstained (3- to 5-micron thick sections), positively charged slides
Storage Instructions
Protect paraffin block and/or slides from excessive heat. Ship in cooled container during summer months.
Causes for Rejection
Specimens submitted with non-representative tissue type. Depleted specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinitely |
| Refrigerated | Indefinitely |
| Frozen | Unacceptable |
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