Antibody Detection RBC with Reflex to ID
Also known as: IRL-ABSC
Use
This test is used to detect the presence of unexpected antibodies directed against red blood cell antigens, which is important in pretransfusion testing, organ and tissue transplantation, evaluation of transfusion reactions, and assessing the risk for hemolytic disease of the fetus and newborn (HDFN). It helps identify potential complications during transfusions and pregnancies.
Special Instructions
Positive screens are reflexed: Female 15-45 years are reflexed to Antibody Identification, RBC (Prenatal Only) (ARUP test code 0013005). All other Positive Screens are reflexed to Antibody ID Package (IRL) (ARUP test code 0013003). Panel identification will be performed on all positive specimens at an additional charge.
Limitations
This test may not detect all clinically significant antibodies, and positive results require further reflex testing to identify the specific antibodies present. Hemagglutination methodology may be affected by factors such as autoimmune hemolytic anemia or recent transfusions, requiring clinical correlation with patient history for accurate interpretation. Separator tubes are unacceptable for testing, and samples may be too small for antibody identification, requiring additional sample submission.
FDA ApprovedNew York Approved
Methodology
Immunoassay (Hemagglutination)
Biomarkers
LOINC Codes
- 14575-5
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
10 mL whole blood (Plain Red) AND 5 mL whole blood (EDTA)
Minimum Volume
7 mL (Plain Red) and 3 mL (EDTA)
Container
Plain Red AND Lavender (K2EDTA) or Pink (K2EDTA)
Storage Instructions
Refrigerated.
Causes for Rejection
Separator tubes
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Unacceptable |
| Refrigerated | 1 week |
| Frozen | Unacceptable |