Direct Antiglobulin Test (DAT) with Reflex to Anti‑C3 and Anti‑IgG

Use

The DAT (Direct Coomb’s test) is positive if red cells have been coated in vivo with immunoglobulin, complement, or both. A positive result may indicate immune‑mediated red cell destruction such as autoimmune hemolytic anemia, a transfusion reaction, or drug‑induced hemolysis.