CD117 (c‑Kit) by Immunohistochemistry
Also known as: CD117 IHC
Use
Immunohistochemical staining for CD117 (c‑Kit) aids in the diagnosis of gastrointestinal stromal tumors (GIST) and other tumors; useful as a diagnostic marker in appropriate clinical context.
Special Instructions
Not provided.
Limitations
Unacceptable specimens include depleted specimens or those submitted with non‑representative tissue type. Do not oven bake precut slides.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
LOINC Codes
- 94736-6 - Tissue block ID Spec
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (Fixed (Non-FFPE))
Volume
Not provided
Minimum Volume
2 slides
Collection Instructions
Formalin fix (10 percent neutral buffered formalin) and paraffin embed specimen (cells must be prepared into a cellblock). Transport tissue block or 5 unstained (3‑ to 5‑micron thick) positively charged slides in a tissue transport kit (ARUP supply #47808). If sending precut slides, do not oven bake.
Storage Instructions
Protect paraffin block and/or slides from excessive heat. Room temperature or refrigerated. Ship in cooled container during summer months.
Causes for Rejection
Depleted specimens. Specimens submitted with non‑representative tissue type.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinitely |
| Refrigerated | Indefinitely |
| Frozen | Indefinitely |
Other tests from different labs that may be relevant