CD117 (c‑Kit) by Immunohistochemistry
Also known as: CD117 IHC
Use
Immunohistochemical staining for CD117 (c‑Kit) aids in the diagnosis of gastrointestinal stromal tumors (GIST) and other tumors; useful as a diagnostic marker in appropriate clinical context.
Special Instructions
This test is performed as a stain‑and‑return (technical) service only. Submit electronic request or use ARUP Immunohistochemistry Stain Form (#32978) if electronic ordering is not available. Refer to ARUP Immunohistochemistry Stain Offerings brochure. Use tissue transport kit (ARUP supply #47808).
Limitations
Unacceptable specimens include depleted specimens or those submitted with non‑representative tissue type. Do not oven bake precut slides.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
LOINC Codes
- 94736-6
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (Fixed (Non-FFPE))
Volume
Not provided
Minimum Volume
2 slides
Collection Instructions
Formalin fix (10 percent neutral buffered formalin) and paraffin embed specimen (cells must be prepared into a cellblock). Transport tissue block or 5 unstained (3‑ to 5‑micron thick) positively charged slides in a tissue transport kit (ARUP supply #47808). If sending precut slides, do not oven bake.
Storage Instructions
Protect paraffin block and/or slides from excessive heat. Room temperature or refrigerated. Ship in cooled container during summer months.
Causes for Rejection
Depleted specimens. Specimens submitted with non‑representative tissue type.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinitely |
| Refrigerated | Indefinitely |
| Frozen | Indefinitely |