Coccidioides Antibodies Panel, Serum
Also known as: COCCI PAN
Use
This test aids in the diagnosis of coccidioidomycosis. It includes a panel of tests that detect Coccidioides antibodies. The presence of these antibodies suggests past or current infection. A titer of 1:2 or greater suggests infection, and titers of less than 1:32 may indicate past infection or self-limited disease. Antibody detection in CSF is diagnostic of coccidioidal meningitis.
Special Instructions
Specimens should be plainly marked as 'acute' or 'convalescent.' Parallel testing of acute and convalescent specimens is preferred, and convalescent specimens must be received within 30 days from receipt of acute specimens.
Limitations
The test may show low sensitivity in cases of chronic residual pulmonary disease, where greater than 30% of patients may have negative CF tests. Titers exceeding 1:16 may indicate disseminated infection. The test also may not detect antibodies in all cases of coccidioidal meningitis.
New York Approved
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 33380-7
- 90448-2
- 27009-0
- 5095-5
Result Turnaround Time
3-6 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
2 mL
Minimum Volume
1.2 mL
Container
ARUP standard transport tube
Collection Instructions
Serum separator tube (SST). Separate from cells ASAP or within 2 hours of collection. Transfer 2 mL serum to an ARUP standard transport tube. Parallel testing is preferred.
Storage Instructions
Refrigerated.
Causes for Rejection
Other body fluids. Contaminated, hemolyzed, icteric, or lipemic specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 year (avoid repeated freeze/thaw cycles) |