Dexamethasone, Serum or Plasma by LC-MS/MS
Also known as: DEXA TMS
Use
This test is used for monitoring compliance with dexamethasone suppression testing, typically in the context of investigating adrenal hyperfunction such as Cushing Syndrome. It helps assess adrenal gland function and diagnose conditions related to high corticosteroid levels.
Special Instructions
Specimen should be collected between 8-10 a.m. and transported to the lab quickly to ensure proper handling and accurate results. The serum or plasma needs to be transferred to an ARUP Standard Transport Tube.
Limitations
This test was developed by ARUP Laboratories as a Laboratory Developed Test (LDT) and it has not been cleared or approved by the US Food and Drug Administration. The performance characteristics were determined by ARUP Laboratories in a CLIA certified laboratory. Results must be interpreted in the context of additional clinical and laboratory findings.
New York Approved
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 14062-4
Result Turnaround Time
2-5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Collect in a serum separator tube, or if not available, plain red, lavender (EDTA), pink (K2EDTA), or green (sodium or lithium heparin) tube can be used. Separate serum or plasma from cells ASAP or within 2 hours of collection.
Patient Preparation
Patient preparation involves collecting the specimen between 8-10 a.m.
Storage Instructions
Refrigerated storage is required for transport.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 24 hours |
| Refrigerated | 1 week |
| Frozen | 6 months |