H3.3 G34W Mutant by Immunohistochemistry
Also known as: H3G34W IHC
Use
The H3.3 G34W Mutant by Immunohistochemistry test is designed to detect the presence of the H3.3 G34W mutation, which is associated with certain types of tumors. This mutation occurs in the histone H3.3 protein and is considered a biomarker for specific tumor types. Identification of this mutation may aid in the diagnosis and classification of these tumors, providing valuable information for clinical decision-making and patient management.
Special Instructions
Not provided.
Limitations
This test is performed as a technical service only, meaning that it serves as a stain and return service. The test has been developed and performance characteristics determined by ARUP Laboratories, but it has not been cleared or approved by the FDA. As such, results should be interpreted by a qualified healthcare professional within the broader context of the patient's clinical situation.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
H3.3 G34W
Protein
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
2 slides
Container
Tissue Transport Kit
Collection Instructions
Formalin fix (10 percent neutral buffered formalin) and paraffin embed specimen (cells must be prepared into a cellblock). Protect paraffin block and/or slides from excessive heat. Transport tissue block or 5 unstained (3- to 5-micron thick sections), positively charged slides.
Storage Instructions
Room temperature. Also acceptable: Refrigerated. Ship in cooled container during summer months.
Causes for Rejection
Specimens submitted with nonrepresentative tissue type. Depleted specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinitely |
| Refrigerated | Indefinitely |
| Frozen | Unacceptable |
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