HBV Exposure Panel
Also known as: HBV EXP
Use
The HBV Exposure Panel is a recommended triple panel test to screen for current or past hepatitis B virus (HBV) infection. This test detects HBV surface antigen (HBsAg), HBV surface antibody (anti-HBs, quantitative), and HBV core total antibodies (anti-HBc total). It provides important diagnostic information for assessing HBV exposure, immunity, and infection status. This panel is crucial in understanding the patient's history of HBV exposure and determining if immunity is present, either through past infection or vaccination.
Special Instructions
Not provided.
Limitations
This assay should not be used for blood donor screening, associated re-entry protocols, or for screening Human Cells, Tissues and Cellular and Tissue-Based Products (HCT/P). False positives can occur, particularly in the HBV core total assay. The test does not differentiate between IgG and IgM antibodies in the HBV core total assay, which can result in an ambiguous interpretation of recent versus remote infection.
FDA ApprovedNew York Approved
Methodology
Immunoassay (CLIA)
Biomarkers
LOINC Codes
- 5196-1 - HBV surface Ag SerPl Ql IA
- 5193-8 - HBV surface Ab SerPl IA-aCnc
- 13952-7 - HBV core Ab SerPl Ql IA
Result Turnaround Time
1-2 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
3.00 mL
Minimum Volume
1.750 mL
Container
Serum separator tube (SST).
Collection Instructions
Separate serum from cells ASAP or within 2 hours of collection.
Storage Instructions
Refrigerated
Causes for Rejection
Heparinized plasma. Specimens containing particulate material or obvious microbial contamination. Heat-inactivated, or severely hemolyzed.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 12 hours |
| Refrigerated | 7 days |
| Frozen | 30 days |
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