Hepatitis C Virus Antibody by CIA with Reflex to HCV by Quantitative NAAT

Casandra

Casandra Test Code AR05028Version 1 (DRAFT)

Performing Lab

Lab ARUP LaboratoriesLab Test ID 2010784CPT Codes 86803, 87522

Hepatitis C Virus Antibody by CIA with Reflex to HCV by Quantitative NAAT

Also known as: HCV AB QR

Clinical Use

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Use

This test is designed to screen and confirm the presence of Hepatitis C Virus (HCV) infection in individuals at risk. It uses a qualitative chemiluminescent immunoassay (CIA) to detect the presence of HCV antibodies. If these antibodies are detected, the test reflexes to a quantitative nucleic acid amplification test (NAAT) to confirm active infection. The detection of HCV RNA through NAAT indicates viral replication, confirming active HCV infection, which aids in diagnosis and management of patients undergoing antiviral therapy.

Special Instructions

A dedicated transport tube is required for the HCV AB QR test. Additional charges apply if the test reflexes to the quantitative NAAT. The test is not suitable for blood donor screening or for screening human cells, tissues, and cellular- and tissue-based products (HCT/P).

Limitations

The test should not be used for blood donor screening, associated reentry protocols, or for screening human cells, tissues, and tissue-based products. A 'Not Detected' result for HCV RNA does not rule out infection, as it may be below the level of detection or the presence of inhibitors may affect the result. Single measurement of viral load should be interpreted in the context of the patient's clinical and laboratory findings.

Test Details

FDA Approved