Insulin Antibody
Also known as: ANTI-INS
Use
This assay is intended for the semi-quantitative determination of antibodies to endogenous insulin or antibodies to exogenous insulin in human serum. Antibodies to exogenous insulin therapies may be detected using this method. The presence of antibodies can be indicative of autoimmune diabetes mellitus (DM), but the magnitude of the result is not related to disease progression. Therefore, results should be interpreted within the context of clinical symptoms.
Special Instructions
Not provided.
Limitations
The test cannot be used to differentiate type 1 diabetes mellitus from type 2 diabetes mellitus in most cases. The presence of antibodies can occur due to the formation of antibodies against exogenous insulin therapies and may not necessarily indicate disease progression. Moreover, plasma samples and hemolyzed or lipemic specimens are unacceptable, which may limit the conditions under which the test can be performed.
FDA ApprovedNew York Approved
Methodology
Immunoassay (RIA)
Biomarkers
Insulin Antibody
Protein
LOINC Codes
- 56546-5 - Insulin Ab Ser IA-aCnc
Result Turnaround Time
2-5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.1 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Collect specimen in a serum separator tube or plain red tube. After separation from cells, transfer serum to an ARUP Standard Transport Tube.
Storage Instructions
Frozen
Causes for Rejection
Plasma, hemolyzed or lipemic specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 24 hours |
| Refrigerated | 1 week |
| Frozen | 2 months |
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