Mammaglobin by Immunohistochemistry
Also known as: MAMMA IHC
Use
Mammaglobin by Immunohistochemistry is utilized to detect the presence of mammaglobin in tissue samples. Its primary clinical significance lies in its use as a biomarker for diagnosing certain types of breast cancer, where mammaglobin expression is often elevated. This test aids in the identification of mammaglobin-expressing cells, providing valuable information for cancer diagnosis and management.
Special Instructions
ARUP Immunohistochemistry Stain Offerings brochure is available for more detailed information on ordering this test. The test requires a formalin-fixed and paraffin-embedded specimen, ideally submitted in a tissue transport kit (ARUP supply #47808). Precut slides should not be oven baked, and excessive heat must be avoided during transport. The test is not performed at ARUP Laboratories; separate specimens are required if multiple tests are ordered.
Limitations
This test is performed as a 'Stain and Return' without interpretation, meaning the test results must be interpreted by a qualified pathologist outside of ARUP Laboratories. It is important to note that specimens with non-representative tissue types or those that are depleted will be rejected. Additionally, the test cannot be performed on frozen tissues and does not accommodate oven-baked slides. Since the test is outsourced, the processing time can vary based on the non-ARUP laboratory's schedule and capacity.
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
3-7 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Tissue transport kit (ARUP supply #47808)
Collection Instructions
Formalin fix (10 percent neutral buffered formalin) and paraffin embed specimen. Protect paraffin block and/or slides from excessive heat.
Storage Instructions
Room temperature. Also acceptable: Refrigerated. Ship in cooled container during summer months
Causes for Rejection
Specimens with non-representative tissue type. Depleted specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinitely |
| Refrigerated | Indefinitely |
| Frozen | Unacceptable |
