Rheumatoid Arthritis (RA) Panel with Reflex to Rheumatoid Factors, IgA, IgG, and IgM by ELISA
Also known as: RA PNL R
Use
The Rheumatoid Arthritis (RA) Panel with Reflex to Rheumatoid Factors, IgA, IgG, and IgM by ELISA aids in the workup of suspected rheumatoid arthritis or undifferentiated inflammatory arthritides. The presence of these antibodies can indicate future RA development and predict radiographic joint destruction. The test helps determine the prognosis by performing rheumatoid factors IgA, IgG, and IgM if anticyclic citrullinated peptide (anti-CCP) IgG or rheumatoid factor is positive.
Special Instructions
Not provided.
Limitations
This test has not been cleared or approved by the US Food and Drug Administration and is intended for clinical purposes in a CLIA-certified laboratory. Unacceptable conditions include contaminated, heat-inactivated, hemolyzed, icteric, or severely lipemic specimens. Stability after separation from cells is: Ambient for 24 hours, Refrigerated for 1 week, and Frozen for 1 month (should not be thawed more than once).
New York Approved
Methodology
Immunoassay (ELISA)
Biomarkers
Carbamylated Protein Antibody, IgG
AnalyteCyclic Citrullinated Peptide Ab, IgG/A
AnalyteRheumatoid Factor
Analyte
LOINC Codes
- 11572-5 - Rheumatoid fact SerPl-aCnc
- 57093-7 - cCP IgA+IgG SerPl IA-aCnc
Result Turnaround Time
1-4 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.8 mL
Container
Serum separator tube (SST); transfer to ARUP standard transport tube
Collection Instructions
Fasting specimen preferred. Allow serum to clot completely at room temperature before centrifuging.
Patient Preparation
Fasting specimen preferred.
Storage Instructions
Refrigerated.
Causes for Rejection
Contaminated, heat-inactivated, hemolyzed, icteric, or severely lipemic specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 24 hours |
| Refrigerated | 1 week |
| Frozen | 1 month (should not be thawed more than once) |
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