Rheumatoid Arthritis (RA) Profile with Reflex to SeroNeg RAdx4
Also known as: RA Profile (Rheumatoid Factor and Anti-CCP) with Reflex to SeroNeg RAdx4 (14-3-3 eta, Anti-CEP1, Anti-Sa, Anti-CarP)
Use
This RA Profile with Reflex to SeroNeg RAdx4 is a novel profile for rheumatoid arthritis that if negative for traditional markers, RF and Anti-CCP, reflexes to 4 novel markers (14-3- eta, Anti-CEP1, Anti-Sa, Anti-CarP) that comprise SeroNeg RAdx4 which is designed to enhance diagnosis of RA and early RA as well as predict disease severity.
Special Instructions
If both Rheumatoid Factor and Anti-CCP are negative, the test reflexes to the SeroNeg RAdx4 panel which includes Anti-MCV, Anti-CEP1, Anti-Sa, and Anti-CarP.
Limitations
The test was developed by Labcorp and its performance characteristics were determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration.
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 11572-5
- 57093-7
- 54022-9
- 96561-6
- 66445-8
Result Turnaround Time
8-11 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
3 mL
Minimum Volume
1 mL
Container
Red-top tube or gel-barrier tube
Collection Instructions
Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping.
Storage Instructions
Refrigerate.
Causes for Rejection
Grossly hemolyzed; bacterial contamination; lipemic, icteric, non-serum specimen types
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 14 days |
| Frozen | 60 days |