Cyclic Citrullinated Peptide (CCP) Antibody (IgG)
Also known as: Citrullinated Peptide (CCP) IgG, CCP, Anti-Cyclic Citrullinated Peptide (CCP) Antibody IgG
Use
A synthetic circular peptide containing citrulline called CCP IgG (cyclic citrullinated peptide) has been found to be better at discriminating Rheumatoid Arthritis patients from patients with other diseases such as hepatitis C infection. Rheumatoid Arthritis Classification Criteria include CCP IgG Antibody, rheumatoid factor, C‑reactive protein and erythrocyte sedimentation rate (ESR). Approximately 70% of patients with Rheumatoid Arthritis are positive for Anti‑CCP IgG, while only about 2% of random blood donors and disease controls subjects are positive.
Special Instructions
Not provided.
Limitations
The presence of immune complexes may cause false‑positive results due to increased non‑specific binding.
Methodology
Immunoassay
Biomarkers
CCP IgG
Protein
Result Turnaround Time
Not provided.
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
Plastic screw‑cap vial
Causes for Rejection
Gross hemolysis • Gross lipemia • Plasma
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 4 days |
| Refrigerated | 7 days |
| Frozen | 30 days |
Other tests from different labs that may be relevant