Carbamylated Protein (CarP) Antibody, IgG
Also known as: CARP IGG
Use
Anti-carbamylated protein (anti-CarP) IgG antibodies are present in about 34-53 percent of patients with RA, have specificities of greater than 90 percent, and can occur in RA patients seronegative for both rheumatoid factor and anti-CCP. These autoantibodies may be present in the preclinical phase of disease, are associated with future RA development, and may predict radiographic joint destruction. Patients with weak positive results should be monitored and testing repeated.
Special Instructions
The preferred test for the workup is the Rheumatoid Arthritis Panel (3016634).
Limitations
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test is intended for clinical purposes and is performed in a CLIA certified laboratory.
New York Approved
Methodology
Immunoassay (ELISA)
Biomarkers
Result Turnaround Time
1-4 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.3 mL
Container
Serum separator tube
Collection Instructions
Separate serum from cells ASAP or within 2 hours of collection. Transfer to an ARUP standard transport tube.
Causes for Rejection
Contaminated, heat-inactivated, hemolyzed, icteric, or lipemic specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 month (avoid repeated freeze/thaw cycles) |