Sal-like 4 (SALL4) by Immunohistochemistry
Also known as: SALL4 IHC
Use
The SALL4 immunohistochemistry test is utilized primarily in the identification and characterization of certain types of tumors. SALL4 is a transcription factor frequently used as a marker in germ cell tumors and some other neoplastic conditions. Through the application of immunohistochemistry methods, the presence of SALL4 within tissue samples can be detected, providing critical information for the diagnosis and management of cancer in a clinical setting.
Special Instructions
Not provided.
Limitations
The test is limited to detection of the SALL4 protein presence using immunohistochemical staining methods. It has not been cleared or approved by the FDA and is executed as a laboratory developed test (LDT) in a CLIA-certified lab. Results should be interpreted within the context of the overall clinical picture, as false positives may occur and stains may not be representative of all tumor cells present.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
SALL4
Protein
LOINC Codes
- 94736-6 - Tissue block ID Spec
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
2 slides
Collection Instructions
Formalin fix (10 percent neutral buffered formalin) and paraffin embed the specimen. Transport the tissue block or 5 unstained (3- to 5-micron thick sections), positively charged slides in an ARUP tissue transport kit (#47808).
Storage Instructions
Store at room temperature or refrigerated. Ship in a cooled container during summer.
Causes for Rejection
Specimens with non-representative tissue type or depleted specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinitely |
| Refrigerated | Indefinitely |
| Frozen | Unacceptable |
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