Thrombin Time with Reflex to Thrombin Time 1:1 Mix
Also known as: TT
Use
This test helps in diagnosing dysfibrinogenemia or abnormalities with fibrin polymerization. It is used to screen samples for the presence of heparin or direct thrombin inhibitors. If the Thrombin Time is elevated, an additional reflex test, Thrombin Time 1:1 Mix, will be performed to further assess the coagulation status.
Special Instructions
Additional charges apply if the reflex test is performed. It is important to ensure the specimen is collected in the appropriate tube and handled according to guidelines. Critical freezing is required for the specimen, and separate specimens must be submitted when multiple tests are ordered.
Limitations
The test is specifically designed for detecting potential thrombin and polymerization abnormalities. However, it may not be fully determinative for all coagulation disorders or exclude all forms of anticoagulant effects. It is important to follow specimen collection and handling instructions to avoid degradation, which could impact results. Hemolyzed or clotted samples lead to rejection.
New York Approved
Methodology
Automated Analyzer (Coagulation)
Biomarkers
LOINC Codes
- 3243-3
- 3243-3
- 33525-7
Result Turnaround Time
1-2 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
2 mL
Minimum Volume
1 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Collect in a Light Blue (Sodium Citrate) tube. Follow specimen handling guidelines for hemostasis/thrombosis.
Storage Instructions
CRITICAL FROZEN. Maintain frozen state during transport.
Causes for Rejection
Serum. EDTA plasma, clotted or hemolyzed specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 4 hours |
| Refrigerated | Unacceptable |
| Frozen | 2 weeks |