Actin (Smooth Muscle) Antibody (ASMA)
Also known as: Antiactin, Smooth Muscle Antibodies
Use
Detection of antibodies aids in the diagnosis of autoimmune liver diseases such as autoimmune hepatitis (AIH) and primary biliary cirrhosis (PBC)
Special Instructions
Test results are generally released within 2 to 3 days after pickup. Additional confirmatory or reflex tests may require more time. Be aware that not all smooth muscle positive samples will have actin antibodies.
Limitations
Antiactin antibodies may be found at low levels in 3% to 18% of healthy individuals, potentially leading to false positives. The presence of immune complexes in the patient's sample may also cause false positive results. Therefore, results should be interpreted in the context of clinical findings and other laboratory tests.
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 44706-0
- 44706-0
Result Turnaround Time
2-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.3 mL
Container
Red-top tube or gel-barrier tube
Storage Instructions
Room temperature
Causes for Rejection
Hemolysis; lipemia; gross bacterial contamination; heat-treated specimen; specimen with preservative added
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |