Smooth Muscle Antibody, IgG Titer
Also known as: *ASM TITER
Use
The Smooth Muscle Antibody, IgG Titer test is helpful in evaluating for autoimmune liver diseases such as autoimmune hepatitis and chronic active hepatitis. The presence of antibodies is suggestive of these conditions, and this test aids in the differential diagnosis by defining antibody levels as negative, weak positive, or positive. Detecting these antibodies can facilitate a more targeted approach in diagnosing associated liver disorders.
Special Instructions
The test is typically ordered when autoimmune liver disease is suspected, and a comprehensive reflex panel may be considered for more thorough diagnostic assessment. Additionally, repeat testing in two to three weeks is suggested for weak positive results, using a fresh specimen to confirm findings.
Limitations
The test is limited by potential interference from contaminated, hemolyzed, or severely lipemic specimens, which could affect accuracy. Weak positive results necessitate follow-up testing to confirm the presence of antibodies. Interpretation of results must consider clinical context, as the presence of antibodies alone does not confirm a diagnosis of autoimmune liver disease. Antibody levels are semi-quantitative and should be correlated with clinical findings.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
LOINC Codes
- 47977-4
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.15 mL
Container
ARUP standard transport tube
Collection Instructions
Separate serum from cells ASAP or within 2 hours of collection.
Storage Instructions
Refrigerated
Causes for Rejection
Contaminated, hemolyzed, or severely lipemic specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 year |