Growth Hormone, Five Specimens
Use
The Growth Hormone, Five Specimens test is crucial for evaluating suspected disorders of growth hormone secretion, such as acromegaly and gigantism. It involves serial measurements of growth hormone levels collected over time to assess hormonal response to stimuli like glucose ingestion or pharmacologic agents. This test is used to diagnose and monitor treatment efficacy for conditions caused by excess or deficiency of growth hormone.
Special Instructions
This test requires multiple tubes drawn at specific intervals after a baseline sample and treatment administration (oral or injection). Biotin interference may affect results; patients must discontinue biotin supplements 72 hours before testing. Coordinate closely with clinicians to ensure appropriate serial specimen collection.
Limitations
Interference can occur if the patient has consumed biotin supplements; results may not be reliable. Additionally, variations in specimen collection timing and processing can affect the interpretation of hormone curves and subsequent diagnosis accuracy.
Methodology
Immunoassay (CLIA)
Biomarkers
LOINC Codes
- 12253-1
- 49892-3
- 27888-7
- 27889-5
- 27881-2
- 46963-5
Result Turnaround Time
4-6 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Collect baseline specimen, administer treatment, and collect subsequent specimens at prescribed times post-treatment.
Patient Preparation
Discontinue biotin supplement at least 72 hours prior.