Immunoglobulin G, Quantitative
Also known as: IgG, Serum, Quantitative IgG, Serum
Use
Evaluate humoral immunity; monitor therapy in IgG myeloma; evaluate patients, especially children and those with lymphoma, with propensity to infections
Special Instructions
Indicate patient's age on the request form. Samples suspected of having macroglobulins or cryoglobulins should be drawn and held at 37°C. Samples suspected of containing cold agglutinins should not be refrigerated prior to serum separation from clot.
Limitations
If samples containing macroglobulins, cryoglobulins, or cold agglutinins are handled incorrectly, false low values may result. Monoclonal gammopathy may be present even when total IgG values are normal, requiring evaluation for other conditions like multiple myeloma and the presence of Bence Jones protein in urine.
Methodology
Immunoassay (Immunoturbidimetric)
Biomarkers
LOINC Codes
- 2465-3
- 2465-3
Result Turnaround Time
1 day
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL (adult), 0.4 mL (pediatric)
Minimum Volume
Not provided
Container
Red-top tube or gel-barrier tube
Collection Instructions
Samples suspected of having macroglobulins or cryoglobulins should be drawn and held at 37°C. Samples suspected of containing cold agglutinins should not be refrigerated prior to serum separation from clot.
Storage Instructions
Room temperature: 14 days; Refrigerated: 14 days; Frozen: 14 days; Stable for 3 freeze/thaw cycles.
Causes for Rejection
Excessive lipemia
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |