Immunoglobulins, Quantitative, IgA, IgE, IgG, IgM

Clinical Use

Use

This test measures the levels of immunoglobulins A, E, G, and M in the blood to help diagnose and monitor immunodeficiencies, allergies, and autoimmune disorders. Immunoglobulins are antibodies produced by the immune system to fight against bacteria, viruses, and other pathogens. Abnormally high or low levels could indicate underlying health conditions that require medical evaluation. The test results can aid in the understanding of a patient's immune response and provides crucial information for treatment planning.

Special Instructions

Not provided.

Limitations

Test results may be affected by high doses of biotin supplements, which can lead to inaccurate values. The stability of the serum sample can also impact the test if not maintained properly as outlined in the storage instructions. Furthermore, results may vary based on the collection and handling of samples suspected of having macroglobulins, cryoglobulins, or cold agglutinins, requiring specific handling to ensure accurate readings. The test is also subject to limitations inherent to immunological assays, such as cross-reactivity and sensitivity constraints.

Test Details

Methodology

Immunoassay (Multiplex Protein Panel)

Biomarkers

4 targets

Immunoglobulin AImmunoglobulin EImmunoglobulin GImmunoglobulin M

LOINC Codes

Order Codes

34550-4 - Immunoglobulin Pnl Ser-mCnc

Result Codes

2465-3 - IgG SerPl-mCnc
2458-8 - IgA SerPl-mCnc
2472-9 - IgM SerPl-mCnc
19113-0 - IgE SerPl-aCnc

Result Turnaround Time

2-4 days

Specimen

Serum

Volume

3 mL

Minimum Volume

Not provided

Container

Red-top tube or gel-barrier tube

Storage Instructions

Samples suspected of having macroglobulins or cryoglobulins should be drawn and held at 37°C. Samples suspected of containing cold agglutinins should not be refrigerated prior to serum separation from clot.