Insulin, Four Specimens

Clinical Use

Use

The Insulin, Four Specimens test is used to monitor insulin levels over multiple time intervals. It involves collecting multiple blood samples from the patient, starting with a baseline sample, followed by treatment with a drug or other treatment (such as glucose administration), and then collecting additional samples at specified time intervals. This test is often used for assessing insulin secretion dynamics in response to a treatment stimulus, providing valuable insights into the patient's insulin regulation and potential metabolic disorders.

Special Instructions

Not provided.

Limitations

The test may show interference if the patient is consuming high levels of biotin, a supplement also known as vitamin B7 or B8. Patients should be asked about biotin intake and advised to cease consumption prior to testing. Additionally, laboratory testing may involve variable schedules and additional time may be necessary for confirmatory tests. Specifications on routine intervals for specimen collection are required to ensure consistent and accurate results.

Test Details

Methodology

Immunoassay (CLIA)

Biomarkers

Insulin

Analyte

Insulin level

Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

LOINC Codes

Order Codes

20448-7 - Insulin SerPl-aCnc
27832-5 - Insulin sp4 p chal SerPl-aCnc
33816-0 - Insulin sp2 p chal SerPl-aCnc
33817-8 - Insulin sp3 p chal SerPl-aCnc
46963-5 - Tube # SerPlBld

Result Codes

20448-7 - Insulin SerPl-aCnc
46963-5 - Tube # SerPlBld
33816-0 - Insulin sp2 p chal SerPl-aCnc
33817-8 - Insulin sp3 p chal SerPl-aCnc
27832-5 - Insulin sp4 p chal SerPl-aCnc

Result Turnaround Time

1-2 days

Specimen

Serum

Volume

2 mL

Minimum Volume

Not provided

Collection Instructions

Label each tube with patient name and time interval. Separate serum from cells within 45 minutes of venipuncture. Submit simultaneously from the same patient on one test request form.