Killer Immunoglobulin-like Receptors (KIR)
Also known as: KIR, KIR Genotyping, KIR SSO Genotyping Test, KIR Typing
Use
The function of natural killer cells in the immune response is regulated by killer immunoglobulin-like receptors (KIR). These receptors interact with class I HLA antigens on the cell surface to prevent or activate killing of the target cell. KIR genotyping may be useful in some stem cell transplants because KIR matching or mismatching can mediate a graft-versus-leukemia effect when the cancer cells are underexpressing HLA class I antigens.
Special Instructions
If you have questions or for assistance in selecting the proper KIR test for the patient, please call HLA customer service at 800-533-1037 or email [email protected].
Limitations
Results for this test are for research purposes only by the assay's manufacturer. The performance characteristics of this product have not been established. Results should not be used as a diagnostic procedure without confirmation of the diagnosis by another medically established diagnostic product or procedure.
Methodology
Microarray
Biomarkers
LOINC Codes
- 64413-8
- 64414-6
- 64415-3
- 64416-1
- 64419-5
- 64420-3
- 64421-1
- 64422-9
- 64423-7
- 64424-5
- 64425-2
- 64426-0
- 64427-8
- 64428-6
- 64429-4
- 64430-2
- 64431-0
- 49549-9
Result Turnaround Time
3-9 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
7 mL
Minimum Volume
3 mL
Container
Lavender-top (EDTA) tube
Storage Instructions
Maintain specimen at room temperature.
Causes for Rejection
Highly lipemic or hemolyzed specimen